SARMs – An effective means for stimulating muscle and bone growth as you age.

SARMs Australia“SARM” is a selective androgen receptor modulator, and there are many of them. There are those that inhibit the androgen receptor so that it doesn’t do its job as well on the nucleus of the cell. There are those that accentuate the effect of the androgen receptor, multiplying the effect. SARMS are “selective” because they work in some cells better than in others. Different SARMs work in different cells in the body.

The SARMs we are interested in for health and longevity and performance are the SARMs that accentuate the effect of testosterone in muscle and bone, but that don’t work in hair and skin and prostate cells throughout the body. The objective is that you don’t experience the side effects typical of testosterone supplementation., rather you just get the benefits.

What is an androgen receptor and how does it work with testosterone?

An androgen receptor is a protein in the cells of your body that testosterone binds to.

When testosterone binds to an androgen receptor molecule, together they move into the nucleus of the cell and they turn on genes in that cell that then tell the cell to do different things. Dependent on what part of the body that cell is, it will do different things.

  • Muscle cells produce contractile proteins = increase in muscle size, strength and mitochondrial proteins will increase energy supply to the cell.
  • Bone cells promote bone growth.
  • Hair cells on the body will promote hair growth.
  • A sebaceous gland in the skin will boost oil production.
  • Prostate cells will promote prostate growth and prostate health.

So the androgen receptor with the testosterone bound to it has effects throughout the body, and it’s important to maintain these effects throughout your life for optimal health and longevity.

SARMS Injection

The SARMs that we have the ability to provide you upon approval are in an injectable form. (SARMs S-22.)

We sell two forms: SARMs S-22 and the SARMs S-22 –forte.

The Ostarine forte is 50% stronger concentration of the SARMs forte, but it’s in an oil base, and the SARMs 22 is in a fluid base.

The liquid base is quite irritating, so while the fluid base requires a thinner diameter to inject, it is a very irritating fluid, and it stings for a few minutes afterwards. It doesn’t do any damage; it just irritates the nerves, and you feel a slight pain, but there is no damage done, and it’s still giving you the SARMs effect. The SARMs Forte, on the other hand, doesn’t have that pain as a side effect; it just needs a larger needle to inject the thicker oil base through.So the SARMs forte binds to the androgen receptor and probably binds to the androgen sensitive genes in the cells of the body.

The Benefits of SARMS Forte (Ostarine)

The SARMS Forte (Ostarine Forte) the S-22, particularly the muscle and bone, and it accentuates the testosterone effects in those tissues.

It’s safe to use in men and women, and it’s used in research done on people with catabolic diseases.

It is used on people with severe burns that require assistance in their tissue repair and growth, and its used for performance and image enhancing purposes.

There are similar molecules called SERMs- selective oestrogen receptor modulators that are used throughout medicine, particularly for stimulating bone cell growth because oestrogen is very good at stimulating bone growth for people who are osteopenic.

SARMS cream 

At Peptide Clinics we now provide SARMs as a cream. It’s a small enough molecule that it’s absorbed through the skin, but as with all creams, not everybody absorbs them well. 10% – 20% of people don’t absorb the creams well, but 80% – 90% do, so that’s another method of absorption if you do not want to inject. One must understand however that when you apply anything to the skin, some of it will get wiped off on clothes or washed off. Not all of it is going to get absorbed. If you use an injection to bypass that skin barrier, then it’s 100% bio-available to the tissues of your body.

SARMs are an effective way for stimulating muscle and bone growth and for maintaining muscle mass and avoiding sarcopenia as you grow older. This helps you avoid osteopenia and osteoporosis as you grow older and loss of bone strength.

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References:

Bhasin, Shalender and Ravi Jasuja. “Selective Androgen Receptor Modulators As Function Promoting Therapies”. Current Opinion in Clinical Nutrition and Metabolic Care 12.3 (2009): 232-240. Web.